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KMID : 0848120130380040175
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International Journal of Oral Biology
2013 Volume.38 No. 4 p.175 ~ p.180
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Effect of Xylitol on various Oral bacteria
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Chung Jin
Na Hee-Sam
Kim Sheon-Min
Kim Se-Yeon
Choi Yoon-Hee
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Abstract
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Xylitol is a five-carbon sugar alcohol that reduces theincidence of caries by inhibiting the growth of oralstreptococci, including Streptococcus mutans. Since xylitolis transported via the fructose phosphotransferase system, wehypothesized that it could also affect the growth of other oralbacteria strains. We tested the effects of xylitol againstnon-periodontopathogenic oral bacteria frequently found inhealthy subjects as well as periodontopathogens includingPorphyromonas gingivalis, Treponema denticola, andTannerella forsythia. With 5% xylitol, Streptococcusvestibularis and Gemella morbillorum showed markedgrowth inhibition. With 10% xylitol, all of the testedperiodontopathogens and Actinomyces naeslundii showedmarked growth inhibition, whereas the growth inhibition ofNeisseria mucosa, Neisseria sicca and Veillonella parvulawas mild only. Xylitol is a widely used sweetener and theconcentration used in our experiment is easily achieved in theoral cavity. If xylitol reduces the growth ofperiodontopathogens more preferentially, it could alsoreduce the prevalence of these pathogens and have clinicalutility in the prevention or treatment of periodontal disease.
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KEYWORD
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Oral bacteria, Periodontopathogen, Xylitol
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